Electron-beam CT: use of a calibration phantom to reduce variability in calcium quantitation.
Electron-beam CT: use of a calibration phantom to reduce variability in calcium quantitation.
复制标题
电子束 CT:使用校准模型来减少钙定量的变异性。
DOI:
10.1148/radiology.196.1.7784560
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发表时间:
1995
期刊:
影响因子:
19.7
通讯作者:
Peyser,PA
中科院分区:
文献类型:
--
作者:
McCollough,CH;Kaufmann,RB;Cameron,BM;Katz,DJ;Sheedy2nd,PF;Peyser,PA
PURPOSETo measure scanner and patient variation in computed tomographic (CT) numbers for electron-beam CT and to determine the ability of calibration phantoms to reduce variability in calcium quantitation.MATERIALS AND METHODSTwo calibration phantoms were imaged to ensure longitudinal homogeneity and to determine the short-term intrascanner variation in CT numbers. Each phantom set was imaged twice a day for 14 weeks to determine intra- and interscanner variation. Data from examinations of 167 patients that included the phantom were analyzed to determine the intra- and interpatient variation in CT numbers of objects with known calcium concentrations.RESULTSThe calibration reduced scanner variations by approximately 25%. The calcium concentration associated with a CT number of 130 HU varied from 77.1 to 136.4 mg/cm3 and was dependent on patient girth, sex, smoking history, and image level.CONCLUSIONScanner and patient variations in CT numbers in electron-beam CT can be reduced with a calibration phantom. In vitro and in vivo estimates of calcium concentration had a precision of 2% and 7%, respectively.