Development of a total hydrocarbon ordinal job-exposure matrix for workers responding to the Deepwater Horizon disaster: The GuLF STUDY.
Development of a total hydrocarbon ordinal job-exposure matrix for workers responding to the Deepwater Horizon disaster: The GuLF STUDY.
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DOI：
10.1038/jes.2017.16
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发表时间：
2018-05
影响因子：
4.5
通讯作者：
Sandler DP
中科院分区：
文献类型：
--
作者：
Stewart PA;Stenzel MR;Ramachandran G;Banerjee S;Huynh TB;Groth CP;Kwok RK;Blair A;Engel LS;Sandler DP
GuLF STUDY 是一项队列研究，旨在调查 2010 年墨西哥湾深水地平线漏油事故应对人员的健康状况。开发空气中总碳氢化合物 (THC)、分散剂和颗粒物的有序工作暴露矩阵 (JEM)，以估计研究参与者的暴露情况。收集了参与者与泄漏相关的任务的信息。暴露组 (EG) 的 JEM 是根据泄漏期间和之后进行的任务和 THC 空气测量结果并使用相关暴露决定因素制定的。为 EG 开发了 THC 算术平均值，分配了序数值，并使用问卷中的决定因素将其与参与者联系起来。采取了不同的方法来合并不同 EG 的风险。分散剂和颗粒物的 EG 基于问卷调查。 EG 之间的 THC 暴露水平存在显着差异。根据参与者在任何工作中经历的最高 THC 水平，约 14% 的受试者被确定属于最高暴露类别。大约 10% 的人群暴露于分散剂或颗粒物。不同EG的暴露之间存在相当大的差异，这有助于研究暴露-反应关系。 JEM 很灵活，允许对几个可能相关的暴露指标进行不同的假设。
The GuLF STUDY is a cohort study investigating the health of workers who responded to the Deepwater Horizon oil spill in the Gulf of Mexico in 2010. To develop an ordinal job-exposure matrix (JEM) of airborne total hydrocarbons (THC), dispersants and particulates to estimate study participants’ exposures. Information was collected on participants’ spill-related tasks. A JEM of exposure groups (EGs) was developed from tasks and THC air measurements taken during and after the spill, using relevant exposure determinants. THC arithmetic means were developed for the EG, assigned an ordinal value, and linked to the participants using determinants from the questionnaire. Different approaches were taken for combining exposures across EGs. EGs for dispersants and particulates were based on questionnaire responses. Considerable differences in THC exposure levels were found among EGs. Based on the maximum THC level participants experienced across any job held, about 14% of the subjects were identified in the highest exposure category. Approximately 10% of the cohort was exposed to dispersants or particulates. Considerable differences were found across exposures of the various EGs, which facilitates investigation of exposure-response relationships. The JEM is flexible to allow for different assumptions about several possibly relevant exposure metrics.
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影响因子：
10.4
作者：
Kwok RK;Engel LS;Miller AK;Blair A;Curry MD;Jackson WB;Stewart PA;Stenzel MR;Birnbaum LS;Sandler DP;GuLF STUDY Research Team
通讯作者：
GuLF STUDY Research Team
影响因子：
--
作者：
Tran Huynh;Ramachandran, Gurumurthy;Stewart, Patricia A.
通讯作者：
Stewart, Patricia A.
影响因子：
--
作者：
Tran Huynh;Quick, Harrison;Stewart, Patricia A.
通讯作者：
Stewart, Patricia A.
影响因子：
8.3
作者：
Morita, A;Kusaka, Y;Kawahara, K
通讯作者：
Kawahara, K
影响因子：
3.3
作者：
Aguilera, Francisco;Mendez, Josefina;Laffon, Blanca
通讯作者：
Laffon, Blanca