Multi-agent concurrent chemoradiotherapy for locally advanced head and neck squamous cell cancer in the elderly

Multi-agent concurrent chemoradiotherapy for locally advanced head and neck squamous cell cancer in the elderly
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DOI:
10.1002/hed.21891
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发表时间:
2012-08-01
影响因子:
2.9
通讯作者:
Ives, Denise I.
Ives, Denise I.
中科院分区:
医学2区
文献类型:
--
作者:
Michal, Stephanie A.;Adelstein, David J.;Ives, Denise I.

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背景头颈部肿瘤患者同步放化疗的获益随年龄增长而减少,这促使了本回顾性研究。方法选择年龄≥ 70岁的局部晚期恶性肿瘤患者,采用以顺铂为基础的同步放化疗方案治疗2个疗程。将临床特征、治疗和结局与相同治疗队列进行比较
Background The reported decreasing benefit with increasing age from concurrent chemoradiotherapy in head and neck cancer patients prompted this retrospective review. Methods Two courses of cisplatin-based concurrent chemoradiotherapy were given to fit patients =70 years with locoregionally advanced cancers. Clinical characteristics, treatment, and outcomes were compared with those for an identically treated cohort