Simultaneous analysis of circulating human cytokines using a high-sensitivity cytokine biochip array
Simultaneous analysis of circulating human cytokines using a high-sensitivity cytokine biochip array
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DOI：
10.1021/pr070409o
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发表时间：
2008-01-01
影响因子：
4.4
通讯作者：
Huxley, Allen
中科院分区：
文献类型：
--
作者：
FitzGerald, S. Pete;McConnell, R. Ivan;Huxley, Allen
生物芯片阵列技术允许使用单个分析设备同时测量每个样本的多个分析物。这项研究表明，它适用于高灵敏度检测12种人循环细胞因子的同时检测。这一应用提高了它们的实时检测能力，保持了较宽的浓度范围，且不影响精度。这种方法在细胞因子研究中是一种非常适用的工具，因为同时测定微量浓度可能是有意义的。
Biochip array technology allows the simultaneous measurement of multiple analytes per sample using a single analytical device. This study shows its applicability to the simultaneous measurement of 12 circulating human cytokines with high-sensitivity detection. This application increases their real-time detectability, maintaining a broad concentration range and without compromising the precision. This methodology represents a very applicable tool in cytokine research when simultaneous determination of minute concentrations can be of interest.