A sub-nanomole level electrochemical method for determination of prochloraz and its metabolites based on medical stone doped disposable electrode
A sub-nanomole level electrochemical method for determination of prochloraz and its metabolites based on medical stone doped disposable electrode
复制标题
基于麦饭石掺杂一次性电极的亚纳摩尔级电化学方法测定咪鲜胺及其代谢物
DOI：
10.1016/j.talanta.2010.10.002
复制
发表时间：
2010-12-15
期刊：
影响因子：
6.1
通讯作者：
Hu, Xiaoya
中科院分区：
文献类型：
--
作者：
Li, Hongbo;Li, Jing;Hu, Xiaoya
首次建立了一种超灵敏、简便的电化学方法，利用纳米孔径麦饭石测定异丙二酚及其代谢物2.4,6-三氯苯酚（2,4,6- tcp）。与未闭合的一次性电极（UDE）相比，纳米孔径麦饭石掺杂一次性电极（MSDDE）不仅显著提高了2,4,6- tcp的氧化峰电流，而且降低了氧化过电位，表明纳米孔径MSDDE可以显著提高2,4,6- tcp的灵敏度。对缓冲液的pH值、纳米孔径麦饭石的含量、积累势和时间等实验条件进行优化，以测定2,4,6- tcp。在最佳条件下，氧化峰电流与2,4,6- tcp浓度在6.0 × 10(-9) ~ 8.0 × 10(-5) mol l范围内成比例。最后，该方法成功地用于检测橙皮中丙氯胺及其代谢物，检出限为8.4 × 10(-10) mol L-1 (0.3 ngg(-1))，并通过气相色谱法验证了该方法的有效性。(C) 2010 Elsevier B.V.版权所有
A ultrasensitive, simple and convenient electrochemical method was firstly developed for the determination of prochloraz and its metabolites as 2.4,6-trichlorophenol (2,4,6-TCP) using nano-aperture medical stone. Compared with the uncloped disposable electrode (UDE), nano-aperture medical stone doped disposable electrode (MSDDE) not only significantly enhances the oxidation peak current of 2,4,6-TCP but also lowers the oxidation overpotential, suggesting that the nano-aperture MSDDE can remarkably improve the sensitivity of 2,4,6-TCP. The experimental conditions such as pH values of buffer solution, the content of nano-aperture medical stone, accumulation potential and time were optimized for the determination of 2,4,6-TCP. At optimal conditions, the oxidation peak current is proportional to the concentration of 2,4,6-TCP over the range from 6.0 x 10(-9) to 8.0 x 10(-5) mol L. Finally, this novel method was successfully employed to detect prochloraz and its metabolites in orange rind with the detection limit of 8.4 x 10(-10) mol L-1 (0.3 ngg(-1)) and the method was validated by gas chromatography. (C) 2010 Elsevier B.V. All rights reserved.