RISK-FACTORS FOR PRIMARY OPEN ANGLE GLAUCOMA

RISK-FACTORS FOR PRIMARY OPEN ANGLE GLAUCOMA
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DOI:
10.1016/s0749-3797(18)31205-4
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发表时间:
1988-03-01
影响因子:
5.5
通讯作者:
SOMMER, A
SOMMER, A
中科院分区:
医学2区
文献类型:
--
作者:
KATZ, J;SOMMER, A

文献摘要

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94名有充分记录的昏迷性视野丧失的个体在年龄、种族和性别上与94名对照组相匹配。两组都完成了关于过去和当前眼部和全身疾病的详细访谈。我们还确定了药物,酒精和香烟的使用。在访谈时测量血压。糖尿病与青光眼关系最密切[比值比,2.80(1.01,7.77)]。高血压和/或药物使用史与青光眼无关,但舒张压升高显示出一定的相关性[比值比,2,.40(0.85,6.81)]。对白人和黑人的单独分析表明,糖尿病是两组的危险因素。在白人中,舒张压和饮酒似乎与青光眼有更强的相关性,但由于可用于亚组分析的人数较少,因此应谨慎解释这些结果。
Ninety-four individuals with well-documented glaucomatous visual field loss were matched by age, race, and sex to 94 controls. Both groups completed a detailed interview about past and current ocular and systemic diseases. We also ascertained medication, alcohol, and cigarette use. Blood pressure measurements were taken at the time of the interview. Diabetes showed the closest association with glaucoma [odds ratio, 2.80 (1.01, 7.77)]. A history of hypertension and/or medication use was not associated with glaucoma, but elevated diastolic blood pressure showed some association [odds ratio, 2,.40 (0.85, 6.81)]. Separate analyses for whites and blacks showed diabetes to be a risk factor for both groups. Diastolic blood pressure and alcohol use appeared to be more strongly associated with glaucoma among whites, but these results should be cautiously interpreted because of the small numbers available for subgroup analysis.