Neuronal Plasticity in the Newborn and Adult Feline Red Nucleus
Neuronal Plasticity in the Newborn and Adult Feline Red Nucleus
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新生儿和成年猫红核的神经元可塑性
DOI：
10.1007/978-3-642-68074-8_6
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发表时间：
1981
影响因子：
2.5
通讯作者：
Y. Fujito
中科院分区：
文献类型：
--
作者：
N. Tsukahara;Y. Fujito
突触可塑性代表了脑损伤后功能恢复的可能机制之一。最近，我们加深了对中央突触可塑性变化本质的了解。轴突萌芽和新突触形成这一显着现象似乎对于功能恢复尤为重要。尽管这种现象在 20 世纪 50 年代首次被证实（Edds 1953），但很难明确地证明中央轴突连接的萌芽。然而，最近的研究提供了令人信服的证据，表明发芽发生在中央突触中，并且新形成的突触具有功能活性（Rais-man 1969；Moore et al. 1971；Steward et al. 1973；Tsukahara et al. 1974；Cotman and Lynch 1976；Lund 1978；Tsukahara 1981）。
Synaptic plasticity represents one of the possible mechanisms of recovery of functions after brain lesions. Recently we have increased our understanding on the nature of plastic changes in the central synapses. One remarkable phenomenon, axonal sprouting and formation of new synapses, seems to be particularly important for the recovery of functions. Although the phenomenon was first demonstrated in the 1950s (Edds 1953), it has been difficult to demonstrate unequivocally sprouting of central axonal connections. However, recent studies provided convincing evidence that sprouting occurs in central synapses and the newly formed synapses are functionally active (Rais-man 1969; Moore et al. 1971; Steward et al. 1973; Tsukahara et al. 1974; Cotman and Lynch 1976; Lund 1978; Tsukahara 1981).