Recurrent nocturnal asthma after exposure to grain dust.
Recurrent nocturnal asthma after exposure to grain dust.
复制标题
接触谷物粉尘后复发性夜间哮喘。
DOI：
10.1164/arrd.1976.114.5.1011
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发表时间：
1976
期刊：
影响因子：
--
通讯作者：
N. M. Schofield
中科院分区：
文献类型：
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作者：
R. Davies;M. Green;N. M. Schofield
一名农民在两次不同的情况下进行了支气管激发试验，试验中他自己的谷物粉尘导致了立即和晚期的呼吸反应，随后，在没有进一步接触谷物粉尘的情况下，在随后的夜晚出现了严重的呼吸反应。对肺功能的研究，包括闭合容积的测量，表明主要涉及大气道和小气道，而不是肺实质。对谷物样本的检查以及皮肤和血清学测试的结果表明，谷物螨（Glycyphagus destructor）可能是一种重要的过敏原。在这些复发性夜间哮喘反应期间，C3 和 C4 的血清浓度没有变化。
Bronchial provocation tests performed on two seperate occasions in a farmer with dust from his own grain led to immediate and late respiratory reactions followed, without further exposure to grain dust, by severe respiratory reactions during subsequent nights. Studies of lung function, including measurements of closing volume, suggested that both large and small airways rather than lung parenchyma were primarily involved. Examination of the grain samples together with the results of skin and serologic tests suggested that the grain mite, Glycyphagus destructor, might be an important allergen. Serum concentrations of C3 and C4 did not alter during these recurrent nocturnal asthmatic reactions.