Target volume definition for upper abdominal irradiation using CT scans obtained during inhale and exhale phases

Target volume definition for upper abdominal irradiation using CT scans obtained during inhale and exhale phases
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DOI:
10.1016/s0360-3016(00)00610-6
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发表时间:
2000-09-01
影响因子:
7
通讯作者:
Ito, H
Ito, H
中科院分区:
医学1区
文献类型:
--
作者:
Aruga, T;Itami, J;Ito, H

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目的:为了评估的治疗规划技术的临床效用,涉及使用静态呼气阶段和静态吸气阶段(两个阶段的规划)的CT图像期间获得的:方法和材料:10例胰腺或肝脏肿瘤进行CT扫描下静态呼气和吸气条件下,经过一段时间的轻度通气。通过设置不同的图像位置,我们能够将两个阶段的图像作为一个数据集进行处理,每个大体肿瘤体积(GTV)分别轮廓,混合GTV用于两个阶段的治疗计划。比较两阶段计划与静态呼气图像计划的治疗效果,计算GTV中心和肾脏中心的偏移量以及GTV的最小剂量。结果:GTV的偏移范围为2.6至27.3 mm,肾脏的偏移范围为2.2至24 mm。在一些使用呼气计划进行治疗的患者中,结论:双期计划是一种简单的技术,可以同时显示肿瘤和器官的运动,使用CT。它进一步确定了肿瘤周围足够的野边缘,并防止关键器官的意外辐射暴露。建议常规使用该技术进行上腹部照射。(C)2000 Elsevier Science Inc.
Purpose: To evaluate the clinical utility of a treatment-planning technique involving the use of CT images obtained during both the static exhalation phase and static inhalation phase (two-phase planning).Methods and Materials: Ten patients with pancreatic or liver tumors underwent CT scanning under static exhale and inhale conditions, after a period of mild ventilation. By setting image positions differently, we were able to treat the two-phase images as one dataset, Each gross tumor volume (GTV) was contoured separately and the mixed GTV was used for the two-phase treatment planning. Treatment plans were constructed to compare the two-phase plans with the plans constructed using static exhalation images, The shift of the center of the GTV and kidneys and the minimum dose of GTV were then calculated,Results: The shift of the GTV ranged from 2.6 to 27.3 mm and that of the kidneys from 2.2 to 24 mm, In some patients whose treatment was planned using exhalation planning, the minimum dose of GTV at inhalation was less than 90% of the isocenter dose.Conclusion: Two-phase planning is a simple technique that can visualize tumor and organ movement simultaneously using CT. It further defines adequate field margins around the tumor and prevents unexpected radiation exposure to critical organs. Routine use of this technique for upper abdominal irradiation is recommended. (C) 2000 Elsevier Science Inc.