Cardiac arrest caused by rapidly increasing ascites in a patient with TAFRO syndrome: a case report
Cardiac arrest caused by rapidly increasing ascites in a patient with TAFRO syndrome: a case report
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DOI：
10.1002/ams2.278
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发表时间：
2017-07-01
影响因子：
1.6
通讯作者：
Shimaoka, Hideki
中科院分区：
文献类型：
--
作者：
Okumura, Masatoshi;Ujiro, Atsushi;Shimaoka, Hideki
案例：血小板减少、全身水肿、发热、肾功能不全和器官肿大（TAFRO）综合征是一种新定义的症状逐渐进展的全身性炎症性疾病。一位59岁男性，因发热及不明原因腹水在普通病房突发休克及呼吸衰竭。紧接着心脏骤停。虽然他被复苏，但需要频繁给予肾上腺素以维持血压。通过从膨胀的腹部引流液体，最有效地稳定了他的循环。当时排出的腹水量达到4,000 mL，持续排出数升>1个月。TAFRO综合征的诊断是基于临床特点和实验室和组织学findings.Outcome：腹水量和浓度的炎症参数减少与治疗使用几种免疫抑制剂。结论：新定义的TAFRO综合征可能是危及生命的。应监测患者是否进展为休克和心脏骤停，特别是腹水迅速增加的患者。
Case: Thrombocytopenia, anasarca, fever, renal insufficiency, and organomegaly (TAFRO) syndrome is a newly defined systemic inflammatory disorder with gradual progression of symptoms. A 59-year-old man with fever and ascites of unknown cause developed sudden-onset shock and respiratory failure in the general ward. Cardiac arrest immediately followed. Although he was resuscitated, frequent administration of adrenaline was required to maintain his blood pressure. His circulation was most effectively stabilized by drainage of fluid from his distended abdomen. The volume of discharged ascites reached 4,000 mL at that time, and several liters continued to be discharged for >1 month. The diagnosis of TAFRO syndrome was based on the clinical features and laboratory and histological findings.Outcome: The ascites volume and concentrations of inflammatory parameters decreased with treatment using several immunosuppressive agents.Conclusion: The newly defined TAFRO syndrome may be life-threatening. Patients should be monitored for progression to shock and cardiac arrest, especially those with rapidly increasing ascites.