New insights into the currently available questionnaire for assessing impaired awareness of hypoglycaemia (IAH) among insulin-treated type 2 diabetes- A key risk factor for hypoglycaemia
New insights into the currently available questionnaire for assessing impaired awareness of hypoglycaemia (IAH) among insulin-treated type 2 diabetes- A key risk factor for hypoglycaemia
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DOI：
10.1016/j.deman.2023.100136
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发表时间：
2023-04-01
期刊：
影响因子：
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通讯作者：
Teh, Ming Ming
中科院分区：
文献类型：
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作者：
Ang, Li Chang;Bee, Yong Mong;Teh, Ming Ming
背景：Gold和Clarke问卷最初用于评估1型糖尿病患者低血糖意识受损（IAH）。本研究探讨了两个问卷之间的异同点时，给予胰岛素治疗的2型糖尿病patients.Methods：共153胰岛素治疗的2型糖尿病患者的平均年龄为61.0 +/- 9.4岁，平均HbA 1c的8.4 +/- 1.5%完成问卷调查，在糖尿病门诊三级医院。采用因子分析法对Clarke问卷的心理测量学特性进行了检验。结果：确定了Clarke问卷的双因素结构，即低血糖意识（因素1）和低血糖经历（因素2）。采用Gold方法，采用斯皮尔曼相关性来检验Clarke问卷的收敛效度。Clarke因子1与Gold评分显著相关（r（s）=0.77，p= 2.5，与Gold法19.6%的相关性相当。结论：Gold单项问卷仅评估低血糖意识，而Clarke问卷同时评估低血糖意识和严重低血糖事件。在胰岛素治疗的2型糖尿病患者中，Gold和Clarke在低血糖意识评估方面具有高度一致性。因此，由于Clarke问卷的双因素性质，这两份问卷相似但不可互换。(c)2023年，任作家。由Elsevier Masson SAS出版。这是CC BY-NC-ND许可下的开放获取文章（http：//creativecommons.org/licenses/by-nc-nd/4.0/）
Background: Gold and Clarke questionnaire are originally developed to assess impaired awareness of hypoglycaemia (IAH) in type 1 diabetes. Present study examined the similarities and differences between the two questionnaires when administered to insulin-treated type 2 diabetes patients.Methods: A total of 153 insulin-treated type 2 diabetes patients with mean age of 61.0 +/- 9.4 years and mean HbA1c of 8.4 +/- 1.5% completed questionnaire in diabetes outpatient clinics of tertiary-care hospital. Factor analysis was conducted to examine the psychometric properties of Clarke questionnaire. Spearman's correlation was used to examine convergent validity of Clarke questionnaire with Gold method.Results: Bifactorial structure for Clarke questionnaire was identified, namely Awareness of Hypoglycaemia (Factor 1) and Experience of Hypoglycaemia (Factor 2). Clarke Factor 1 correlated strongly with Gold scores (r(s)=0.77, p= 2.5, which is comparable to Gold method of 19.6%.Conclusions: Gold single-item questionnaire assesses hypoglycaemia awareness only while Clarke questionnaire assesses both hypoglycaemia awareness and severe hypoglycaemia events. There is a high degree of convergence between Gold and Clarke in hypoglycaemia awareness assessment among insulin-treated type 2 diabetes. Hence, these two questionnaires are similar but not interchangeable due to bifactorial nature of Clarke questionnaire.(c) 2023 The Authors. Published by Elsevier Masson SAS. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)