Large-scale comparative neuroimaging: Where are we and what do we need?
Large-scale comparative neuroimaging: Where are we and what do we need?
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DOI：
10.1016/j.cortex.2018.11.028
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发表时间：
2019-09-01
期刊：
影响因子：
3.6
通讯作者：
Mars, Rogier B.
中科院分区：
文献类型：
--
作者：
de Schotten, Michel Thiebaut;Croxson, Paula L.;Mars, Rogier B.
神经成像可以为比较神经科学提供很多东西。尽管侵入性“金标准”技术具有更好的空间分辨率，但神经成像允许对活体动物和死后组织进行快速、全脑、可重复和多模态的结构和功能测量。在过去的几年里，比较神经成像越来越受欢迎。然而，我们认为，它最重要的潜力在于它能够收集许多物种的大规模数据集，以研究整个物种的大脑组织变异性原理——这是一个目前尚未实现但可以实现的雄心。我们简要回顾了该领域的现状，并探讨了目前这种方法的障碍是什么。我们提出了一些行动呼吁。(C) 2019作者。Elsevier Ltd.出版。
Neuroimaging has a lot to offer comparative neuroscience. Although invasive "gold standard" techniques have a better spatial resolution, neuroimaging allows fast, whole-brain, repeatable, and multi-modal measurements of structure and function in living animals and post-mortem tissue. In the past years, comparative neuroimaging has increased in popularity. However, we argue that its most significant potential lies in its ability to collect large-scale datasets of many species to investigate principles of variability in brain organisation across whole orders of species-an ambition that is presently unfulfilled but achievable. We briefly review the current state of the field and explore what the current obstacles to such an approach are. We propose some calls to action. (C) 2019 The Authors. Published by Elsevier Ltd.