EFFECTS OF AGING ON VISUAL EVOKED-RESPONSES

EFFECTS OF AGING ON VISUAL EVOKED-RESPONSES
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DOI:
10.1001/archneur.1977.00500190037005
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发表时间:
1977-01-01
影响因子:
--
通讯作者:
DALY, RF
DALY, RF
中科院分区:
其他
文献类型:
--
作者:
CELESIA, GG;DALY, RF

文献摘要

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在 74 名 18-79 岁的志愿者中研究了衰老对视觉诱发反应 (VER) 和光驱动临界频率 (CFPD) 的影响。 VER 模式逆转刺激的幅度不随性别或年龄而变化。随着年龄的增长,VER 的第一主要负偏转和第一主要正偏转的潜伏期显着延迟(P < 0.001)。这种潜伏期的增加可能反映了视神经或视通路或两者的传导速度减慢。 CFPD 定义为以每秒闪光次数表示的光驱动反应的最高频率,显示出负相关性,在老年受试者中随着年龄的增长而降低。光驱动的临界频率是临界闪烁融合的电生理学对应物,已知它会随着年龄的增长而降低。衰老显然会影响专门感觉系统的功能。
The effects of aging on visual evoked responses (VER) and critical frequency of photic driving (CFPD) was studied in 74 volunteers aged 18-79. The amplitude of VER to pattern reversal stimulation did not vary with sex or age. The latencles of the 1st major negative and of the 1st major positive deflection of the VER were significantly delayed (P < 0.001) with advancing age. This increase of latency probably reflects a slowing of conduction velocity in the optic nerve or optic pathways or both. CFPD, defined as the highest frequency of photic driving response expressed in flashes per second, showed an inverse correlation, decreasing with age in older subjects. Critical frequency of photic driving is the electrophysiological counterpart of critical flicker fusion, which is known to decrease with advancing age. Aging apparently influences the functions of specialized sensory systems.