Does Increasing Steps Per Day Predict Improvement in Physical Function and Pain Interference in Adults With Fibromyalgia?
Does Increasing Steps Per Day Predict Improvement in Physical Function and Pain Interference in Adults With Fibromyalgia?
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DOI：
10.1002/acr.22398
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发表时间：
2014-12-01
影响因子：
4.7
通讯作者：
Ang, Dennis C.
中科院分区：
文献类型：
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作者：
Kaleth, Anthony S.;Slaven, James E.;Ang, Dennis C.
Objective.研究纤维肌痛（FM）患者每天行走步数与临床结局之间的并发性和预测性相关性。共有199名患有FM的成年人（平均年龄46.1岁，95%为女性），在一项随机临床试验中佩戴髋关节加速计1周，并完成身体功能的自我报告测量。（纤维肌痛影响量表-身体损害[FIQ-PI]，简表36 [SF-36]健康调查身体成分评分[PCS]，疼痛强度和干扰（简明疼痛量表[BPI]）和抑郁症状（患者健康问卷-8（PHQ-8））作为其基线和随访评估的一部分。从基线到第12周，每天的步数与自我报告的临床指标的相关性通过多变量回归模型进行评估，该模型调整了人口统计学和基线协变量。研究参与者主要是久坐不动。平均每天4,019 +/- 1,530步。我们的研究结果表明，FM每天步数的变化与健康结果的改善之间存在线性关系。每天1000步的增量与FIQ-PI、SF-36 PCS、BPI疼痛干扰和PHQ-8的改善显著相关（并具有预测性）（均P < 0.05）。虽然较高的步数与较低的FIQ和BPI疼痛强度评分相关，但这些差异无统计学意义。步数是一种容易获得和理解的日常身体活动的客观衡量标准。运动处方包括建议每天逐渐累积至少5，000步的额外步骤，可能会导致FM患者相关结局的临床显著改善。未来的研究需要阐明FM患者每天的步数与患者结局之间的剂量-反应关系。
Objective. To examine the concurrent and predictive associations between the number of steps taken per day and clinical outcomes in patients with fibromyalgia (FM).Methods. A total of 199 adults with FM (mean age 46.1 years, 95% women) who were enrolled in a randomized clinical trial wore a hip-mounted accelerometer for 1 week and completed self-report measures of physical function (Fibromyalgia Impact Questionnaire-Physical Impairment [FIQ-PI], Short Form 36 [SF-36] health survey physical component score [PCS], pain intensity and interference (Brief Pain Inventory [BPI]), and depressive symptoms (Patient Health Questionnaire-8 [PHQ-8]) as part of their baseline and followup assessments. Associations of steps per day with self-report clinical measures were evaluated from baseline to week 12 using multivariate regression models adjusted for demographic and baseline covariates.Results. Study participants were primarily sedentary. averaging 4,019 +/- 1,530 steps per day. Our findings demonstrate a linear relationship between the change in steps per day and improvement in health outcomes for FM. Incremental increases on the order of 1.000 steps per day were significantly associated with (and predictive of) improvements in FIQ-PI, SF-36 PCS, BPI pain interference, and PHQ-8 (all P < 0.05). Although higher step counts were associated with lower FIQ and BPI pain intensity scores, these were not statistically significant.Conclusion. Step count is an easily obtained and understood objective measure of daily physical activity. An exercise prescription that includes recommendations to gradually accumulate at least 5,000 additional steps per day may result in clinically significant improvements in outcomes relevant to patients with FM. Future studies are needed to elucidate the dose-response relationship between steps per day and patient outcomes in FM.