SQUID-Based Microtesla MRI for In Vivo Relaxometry of the Human Brain
SQUID-Based Microtesla MRI for In Vivo Relaxometry of the Human Brain
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DOI：
10.1109/tasc.2009.2018764
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发表时间：
2009-06-01
影响因子：
1.8
通讯作者：
Espy, Michelle A.
中科院分区：
文献类型：
--
作者：
Zotev, Vadim S.;Matlashov, Andrei N.;Espy, Michelle A.
在过去几年中，微特斯拉场的基于SQUID的MRI（磁共振成像）得到了显着发展。在这里，我们描述了应用这种方法的磁弛豫测量在活的人脑。我们报告的值的纵向弛豫时间T1的脑组织，在体内测量的第一次在微特斯拉领域。实验在46 μ T场使用设计用于微特斯拉MRI和MEG的七通道SQUID系统进行。T1的值，测量不同的组织在这个领域，被发现是接近（5%以内）的横向弛豫时间T2在同一领域的相应值。这一结果的影响，在微特斯拉MRI成像对比度进行了讨论。
SQUID-based MRI (magnetic resonance imaging) at microtesla fields has developed significantly over the past few years. Here we describe application of this method for magnetic relaxation measurements in the living human brain. We report values of the longitudinal relaxation time T1 for brain tissues, measured in vivo for the first time at microtesla fields. The experiments were performed at 46 mu T field using a seven-channel SQUID system designed for microtesla MRI and MEG. Values of T1, measured for different tissues at this field, are found to be close (within 5%) to the corresponding values of the transverse relaxation time T2 at the same field. Implications of this result for imaging contrast in microtesla MRI are discussed.