Oxidative cross-coupling of acrylates with vinyl carboxylates catalyzed by a Pd(OAc)2/HPMoV/O2 system
Oxidative cross-coupling of acrylates with vinyl carboxylates catalyzed by a Pd(OAc)2/HPMoV/O2 system
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DOI：
10.1021/ol047971u
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发表时间：
2004-11-25
期刊：
影响因子：
5.2
通讯作者：
Ishii, Y
中科院分区：
文献类型：
--
作者：
Hatamoto, Y;Sakaguchi, S;Ishii, Y
[图表]丙烯酸酯与羧酸乙烯酯的氧化交叉偶联首次通过使用Pd（OAc）（2）/HPMoV/O-2系统以相当好的产率成功实现。例如，丙烯酸正丁酯与醋酸乙烯酯在催化量的钯（乙酸）（2）和氢（4）PMo（11）Vo（40）（.）存在下的反应nH（2）O在O-2存在下在乙酸中于70 ℃反应121 n得到相应的交叉偶联产物5-（乙酰氧基）-2，4-异辛酸正丁酯，产率70%。
[GRAPHICS]Oxidative cross-coupling of acrylates with vinyl carboxylates was first successfully achieved by the use of a Pd(OAc)(2)/HPMoV/O-2 system in fair to good yields. For instance, the reaction of n-butyl acrylate with vinyl acetate in the presence of catalytic amounts of Pd(OAc)(2) and H(4)PMo(11)Vo(40)(.)nH(2)O under O-2 in acetic acid at 70 degreesC for 12 In afforded the corresponding cross-coupling product, n-butyl 5-(acetoxy)-2,4-pentadienoate, in 70% yield.