The potential benefit of stem cell therapy after stroke: an update.
The potential benefit of stem cell therapy after stroke: an update.
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DOI：
10.2147/vhrm.s25745
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发表时间：
2012
影响因子：
2.9
通讯作者：
Chataway J
中科院分区：
文献类型：
--
作者：
Banerjee S;Williamson DA;Habib N;Chataway J
视频中风是全球死亡和残疾的主要原因。干细胞治疗是一种新兴的治疗方式，在临床前中风模型中有显著益处的证据。一些第一和第二阶段的临床试验现已完成，还有几个正在进行中。然而，将其转化为临床研究还有很长的路要走，还有许多问题没有得到解答。本综述将总结目前的证据和全球正在进行的临床试验，并探讨使其成为未来现实治疗选择的挑战。
Video Stroke is a leading cause of death and disability worldwide. Stem cell therapy is an emerging therapeutic modality with evidence of significant benefits in preclinical stroke models. A number of phase I and II clinical trials have now been completed, with several more currently under way. Translation to the bedside, however, remains a long way off, and there are many questions that remain unanswered. This review will summarize the current evidence and ongoing clinical trials worldwide, and explore the challenges to making this a realistic treatment option for the future.