A cortical representation of the local visual environment
A cortical representation of the local visual environment
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DOI：
10.1038/33402
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发表时间：
1998-04-09
期刊：
影响因子：
64.8
通讯作者：
Kanwisher, N
中科院分区：
文献类型：
--
作者：
Epstein, R;Kanwisher, N
内侧颞叶脑区，如海马区和海马旁皮层，通常与导航（1-6）和视觉记忆（7-9）有关。然而，这些区域的具体功能尚不清楚。在这里，我们提供的证据表明，人类海马旁皮层的一个特定区域参与了导航的一个关键组成部分：在功能性磁共振成像（fMRI）中，我们将这个区域称为“海马体旁区”（PPA），它对被动观看的场景有选择性地、自动地做出反应，但对单个物体的反应很弱，对人脸的反应则完全没有。这种激活的关键因素似乎是存在于有关局部空间布局的信息刺激中。PPA对有空间布局但没有离散物体的场景（空房间）的反应与包含多个物体的复杂有意义的场景（布置相同的房间）的反应一样强烈，是对没有三维空间背景的多个物体阵列（这些房间的家具在空白背景上）的反应的两倍多。如果场景中的表面被重新排列，使它们不再定义一个连贯的空间，那么这种响应就会减少。我们建议PPA通过编码当地环境的几何形状来表示地点。
Medial temporal brain regions such as the hippocampal formation and parahippocampal cortex have been generally implicated in navigation(1-6) and visual memory(7-9). However, the specific function of each of these regions is not yet clear, Here we present evidence that a particular area within human parahippocampal cortex is involved in a critical component of navigation: perceiving the local visual environment, This region, which we name the 'parahippocampal place area' (PPA), responds selectively and automatically in functional magnetic resonance imaging (fMRI) to passively viewed scenes, but only weakly to single objects and not at all to faces, The critical factor for this activation appears to be the presence in the stimulus of information about the layout of local space. The response in the PPA to scenes with spatial layout but no discrete objects (empty rooms) is as strong as the response to complex meaningful scenes containing multiple objects (the same rooms furnished) and over twice as strong as the response to arrays of multiple objects without three-dimensional spatial context (the furniture from these rooms on a blank background). This response is reduced if the surfaces in the scene are rearranged so that they no longer define a coherent space, We propose that the PPA represents places by encoding the geometry of the local environment.