Post-traumatic stress disorder, depression and suicidality in inpatients with substance use disorders
Post-traumatic stress disorder, depression and suicidality in inpatients with substance use disorders
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DOI：
10.1111/j.1465-3362.2011.00314.x
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发表时间：
2012-05-01
影响因子：
3.8
通讯作者：
Farrugia, Philippa
中科院分区：
文献类型：
--
作者：
Dore, Glenys;Mills, Katherine;Farrugia, Philippa
介绍和目标。国际文献表明，创伤性事件在物质使用障碍（SUD）患者中很常见，并且通常与创伤后应激障碍（PTSD）和其他精神病合并症的发展相关。然而，在澳大利亚SUD患者中进行的研究有限。本研究的目的是研究这些疾病的患病率在一组澳大利亚患者入院戒毒。设计和方法。数据收集从253名住院患者使用的复合国际诊断访谈，10项创伤筛查问卷，Zung抑郁自评量表和问题的PsyCheck的修改版本。结果大约20%的住院患者经历了中度至重度抑郁症状，37%的患者有自我伤害或企图自杀的终身史。大约80%的患者经历过至少一次创伤事件，大多数经历过多次创伤。首次创伤的平均年龄为14岁。近45%的患者对当前的PTSD症状筛查呈阳性。妇女被强奸的可能性是男子的九倍，被性骚扰的可能性是男子的五倍。创伤后应激障碍症状与更大的创伤暴露、更年轻的首次创伤年龄、特定的创伤类型、中度至重度抑郁症状以及自我伤害或自杀未遂史相关。尽管有困难，但有PTSD症状的患者在治疗中的保留率很高。讨论和结论。接受SUD治疗的患者应评估PTSD、抑郁和自杀倾向。这些情况对治疗结果有显著影响，需要制定适当的治疗策略。[Dore G，米尔斯K，默里R，Teesson M，Farrugia P.物质使用障碍住院患者的创伤后应激障碍，抑郁和自杀。药物酒精Rev 2012;31：294-302]
Introduction and Aims. The international literature suggests that traumatic events are common for patients with substance use disorders (SUDs), and are often associated with the development of post-traumatic stress disorder (PTSD) and other psychiatric comorbidities. However, limited research has been conducted among Australian SUD patients. The aim of the present study was to examine the prevalence of these disorders in a group of Australian patients admitted for detoxification. Design and Methods. Data were collected from 253 inpatients using a modified version of the Composite International Diagnostic Interview, the 10-item Trauma Screening Questionnaire, the Zung Self-rating Depression Scale and questions from the PsyCheck. Results. Approximately 20% of inpatients experienced moderate to severe depressive symptoms, and 37% had a lifetime history of self-harm or attempted suicide. Approximately 80% of patients had experienced at least one traumatic event, most experiencing multiple traumas. The mean age of first trauma was 14 years. Almost 45% of patients screened positive for current PTSD symptoms. Women were nine times more likely to have been raped and five times more likely to have been sexually molested than men. PTSD symptoms were associated with greater trauma exposure, younger age of first trauma, specific trauma types, moderate to severe depressive symptoms and a history of self-harm or attempted suicide. Despite their difficulties, patients with PTSD symptoms had high rates of retention in treatment. Discussion and Conclusions. Patients entering treatment for SUDs should be assessed for PTSD, depression and suicidality. These conditions impact significantly on treatment outcomes, and require the development of appropriate treatment strategies. [Dore G, Mills K, Murray R, Teesson M, Farrugia P. Post-traumatic stress disorder, depression and suicidality in inpatients with substance use disorders. Drug Alcohol Rev 2012;31:294-302]