Real-time 3D and 4D Fourier domain Doppler optical coherence tomography based on dual graphics processing units.

Real-time 3D and 4D Fourier domain Doppler optical coherence tomography based on dual graphics processing units.
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DOI:
10.1364/boe.3.002162
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发表时间:
2012-09-01
影响因子:
3.4
通讯作者:
Kang JU
Kang JU
中科院分区:
医学2区
文献类型:
--
作者:
Huang Y;Liu X;Kang JU

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我们提出了实时3D(2D横截面图像加时间)和4D(3D体积加时间)相位分辨多普勒OCT(PRDOCT)成像的基础上配置的双图形处理器(GPU)。设计并实现了一种基于GPU加速的相位分辨处理算法。我们结合了基于图像强度的结构阈值掩模和平均窗口方法来提高多普勒相位图像的信噪比。图像大小为1000 × 1024(X × Z)像素,帧速率为70 fps。组织结构和血流图像的3D体积绘制-每个尺寸为512 × 512像素-在每个体积扫描周期后64.9毫秒呈现,体积尺寸为500 × 256 × 512(X × Y × Z)体素,采集时间窗口仅为3.7秒。据我们所知,这是第一次实现了在线、同步的结构和多普勒血流体积可视化。测得的最大系统处理速度为每秒249,000次A扫描,每次A扫描尺寸为2048像素。
We present real-time 3D (2D cross-sectional image plus time) and 4D (3D volume plus time) phase-resolved Doppler OCT (PRDOCT) imaging based on configuration of dual graphics processing units (GPU). A GPU-accelerated phase-resolving processing algorithm was developed and implemented. We combined a structural image intensity-based thresholding mask and average window method to improve the signal-to-noise ratio of the Doppler phase image. A 2D simultaneous display of the structure and Doppler flow images was presented at a frame rate of 70 fps with an image size of 1000 × 1024 (X × Z) pixels. A 3D volume rendering of tissue structure and flow images—each with a size of 512 × 512 pixels—was presented 64.9 milliseconds after every volume scanning cycle with a volume size of 500 × 256 × 512 (X × Y × Z) voxels, with an acquisition time window of only 3.7 seconds. To the best of our knowledge, this is the first time that an online, simultaneous structure and Doppler flow volume visualization has been achieved. Maximum system processing speed was measured to be 249,000 A-scans per second with each A-scan size of 2048 pixels.