MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense.
MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense.
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植物防御和病毒反防御中 MicroRNA 介导的基因沉默
DOI：
10.3389/fmicb.2017.01801
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发表时间：
2017
影响因子：
5.2
通讯作者：
Zhang JZ
中科院分区：
文献类型：
--
作者：
Liu SR;Zhou JJ;Hu CG;Wei CL;Zhang JZ
MicroRNAs (miRNAs) are non-coding RNAs of approximately 20–24 nucleotides in length that serve as central regulators of eukaryotic gene expression by targeting mRNAs for cleavage or translational repression. In plants, miRNAs are associated with numerous regulatory pathways in growth and development processes, and defensive responses in plant–pathogen interactions. Recently, significant progress has been made in understanding miRNA-mediated gene silencing and how viruses counter this defense mechanism. Here, we summarize the current knowledge and recent advances in understanding the roles of miRNAs involved in the plant defense against viruses and viral counter-defense. We also document the application of miRNAs in plant antiviral defense. This review discusses the current understanding of the mechanisms of miRNA-mediated gene silencing and provides insights on the never-ending arms race between plants and viruses.
