Physical and mental health status of older long-term cancer survivors
Physical and mental health status of older long-term cancer survivors
复制标题
DOI：
10.1111/j.1532-5415.2005.00507.x
复制
发表时间：
2005-12-01
影响因子：
6.3
通讯作者：
Meara, E
中科院分区：
文献类型：
--
作者：
Keating, NL;Norredam, M;Meara, E
目的：评估老年长期癌症幸存者的身心健康状况。设计：队列研究，使用倾向评分法来控制癌症幸存者和对照组之间的基线差异。研究对象：美国普通社区人群。参与者：964名存活超过4年的癌症患者和14333名从未患过癌症的对照患者，这些患者来自于2002年健康与退休研究的55岁及以上的美国人。测量：医疗条件、症状、健康行为、健康状况、活动能力、日常生活活动、心理健康诊断、自评记忆、抑郁症状、认知功能和自我报告的预期寿命。结果：癌症幸存者报告的肺部疾病（13.9% vs 9.6%, P = 0.001）、心脏病（29.3% vs 22.9%, P < 0.001）、关节炎（69.4% vs 59.4%, P < 0.001）、尿失禁（26.6% vs 19.7%, P = 0.001）、频繁疼痛（36.4% vs 29.4%, P = 0.005）和肥胖（27.0% vs 24.2%, P = 0.001）的比例高于非癌症个体，但吸烟率较低（12.0% vs 14.8%, P = 0.03）。与没有癌症的人相比，癌症幸存者报告良好或非常好的健康状况的可能性更小（37.2% vs 44.6%; P < .001），并且有更多的流动性（P < .001）和日常生活活动（P = .01）限制。癌症幸存者在抑郁和认知功能方面与未患癌症的人没有差异（P均为0.05），但对他们的预期寿命不太乐观（P = 0.004）。结论：老年长期癌症幸存者的身体健康状况略差于从未患过癌症的可比人群，但他们的心理健康状况却惊人地相似。未来的研究需要了解导致较差健康状况的因素，并确定长期癌症相关问题风险最高的患者。
OBJECTIVES: To assess the physical and mental health status of older long-term cancer survivors.DESIGN: Cohort study using propensity score methods to control for baseline differences between cancer survivors and controls.SETTING: General community population in the United States.PARTICIPANTS: Nine hundred sixty-four cancer patients who had survived for more than 4 years and 14,333 control patients who had never had cancer from a population-based sample of Americans aged 55 and older responding to the 2002 Health and Retirement Study.MEASUREMENTS: Medical conditions, symptoms, health behaviors, health status, mobility, activities of daily living, mental health diagnoses, self-rated memory, depressive symptoms, cognitive function, and self-reported life expectancy.RESULTS: Cancer survivors reported higher rates of lung disease (13.9% vs 9.6%; P = .001), heart condition (29.3% vs 22.9%; P < .001), arthritis (69.4% vs 59.4%; P < .001), incontinence (26.6% vs 19.7%; P = .001), frequent pain (36.4% vs 29.4%; P = .005), and obesity (27.0% vs 24.2%; P = .001) than individuals without cancer but lower rates of smoking (12.0% vs 14.8%; P = .03). Cancer survivors were less likely than persons without cancer to report excellent or very good health status (37.2% vs 44.6%; P < .001) and had more mobility (P < .001) and activity of daily living (P = .01) limitations. Cancer survivors did not differ from persons without cancer in rates of depression or cognitive function (both P > .2) but were less optimistic about their life expectancy (P = .004).CONCLUSION: The physical health status of older long-term cancer survivors is somewhat worse than that of comparable persons who have never had cancer, but they have surprisingly similar mental health status. Future research is needed to understand factors contributing to poorer health status and identify patients at highest risk of long-term cancer-related problems.