Palladium-catalyzed formal [4+2] cycloaddtion of o-xylylenes with olefins.
Palladium-catalyzed formal [4+2] cycloaddtion of o-xylylenes with olefins.
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DOI：
10.1021/ja070012l
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发表时间：
2007-03
影响因子：
15
通讯作者：
R. Kuwano;T. Shige
中科院分区：
文献类型：
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作者：
R. Kuwano;T. Shige
以Pd(η3-C3H5)Cp和1,2-双（二苯基膦）乙烷（DPPE）为原料，在钯催化剂的存在下，原位生成了o-（硅甲基）碳酸苄酯与多种共轭烯烃反应。该反应产率高，可提供2-和/或3-取代四联胺。这里描述的催化反应相当于邻二甲苯与亲二酚的[4+2]环加成反应。
o-(Silylmethyl)benzylic carbonates reacted with various conjugated olefins in the presence of the palladium catalyst, which was generated in situ from Pd(η3-C3H5)Cp and 1,2-bis(diphenylphosphino)ethane (DPPE). The reaction provided 2- and/or 3-substituted tetralins in good yield. The catalytic reaction described here is equivalent to the [4+2] cycloaddition of o-xylylenes with dienophiles.