4-(N,N-dimethylamine)benzonitrile (DMABN) derivatives with boronic acid and boronate groups:: new fluorescent sensors for saccharides and fluoride ion
4-(N,N-dimethylamine)benzonitrile (DMABN) derivatives with boronic acid and boronate groups:: new fluorescent sensors for saccharides and fluoride ion
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DOI：
10.1039/b618183j
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发表时间：
2007-01-01
影响因子：
--
通讯作者：
Zhu, Daoben
中科院分区：
文献类型：
--
作者：
Tan, Wei;Zhang, Deqing;Zhu, Daoben
设计并合成了两个分别具有1和2个硼酸/硼酸基的DMABN衍生物，分别用于传感糖和F-。观察了1与果糖、半乳糖、甘露糖和葡萄糖反应后的荧光光谱变化，并估算了相应的结合常数。结果表明，化合物1对果糖的结合力强于其它糖类。有趣的是，在加入F-后，化合物2的吸收光谱和荧光光谱都发生了变化，表明化合物2是一种潜在的选择性F-传感器。
Two DMABN derivatives with boronic acid/boronate groups 1 and 2 were designed and synthesized for sensing saccharides and F-, respectively. Fluorescent spectral changes were observed for 1 after reaction with fructose, galactose, mannose and glucose, and the corresponding binding constants were estimated. The results show that compound 1 can bind fructose more strongly than other saccharides tested. Interestingly, both absorption and fluorescence spectral changes occurred for compound 2 after addition of F-, indicating that compound 2 is a potentially selective sensor for F-.