Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats.
Creatine supplementation spares muscle glycogen during high intensity intermittent exercise in rats.
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DOI：
10.1186/1550-2783-7-6
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发表时间：
2010-01-29
影响因子：
5.1
通讯作者：
Lancha AH Jr
中科院分区：
文献类型：
--
作者：
Roschel H;Gualano B;Marquezi M;Costa A;Lancha AH Jr
The effects of creatine (CR) supplementation on glycogen content are still debatable. Thus, due to the current lack of clarity, we investigated the effects of CR supplementation on muscle glycogen content after high intensity intermittent exercise in rats. First, the animals were submitted to a high intensity intermittent maximal swimming exercise protocol to ensure that CR-supplementation was able to delay fatigue (experiment 1). Then, the CR-mediated glycogen sparing effect was examined using a high intensity intermittent sub-maximal exercise test (fixed number of bouts; six bouts of 30-second duration interspersed by two-minute rest interval) (experiment 2). For both experiments, male Wistar rats were given either CR supplementation or placebo (Pl) for 5 days. As expected, CR-supplemented animals were able to exercise for a significant higher number of bouts than Pl. Experiment 2 revealed a higher gastrocnemius glycogen content for the CR vs. the Pl group (33.59%). Additionally, CR animals presented lower blood lactate concentrations throughout the intermittent exercise bouts compared to Pl. No difference was found between groups in soleus glycogen content. The major finding of this study is that CR supplementation was able to spare muscle glycogen during a high intensity intermittent exercise in rats.
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DOI：
10.1249/01.mss.0000233790.08788.3e
发表时间：
2006-11-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Cribb, Paul J.;Hayes, Alan
通讯作者：
Hayes, Alan
影响因子：
5.5
作者：
Ceddia, RB;Sweeney, G
通讯作者：
Sweeney, G
DOI：
10.1097/00005768-199704000-00010
发表时间：
1997-04-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Brannon, TA;Adams, GR;Baldwin, KM
通讯作者：
Baldwin, KM
影响因子：
4.5
作者：
Gallo, Maria;Gordon, Tessa;Putman, Charles T.
通讯作者：
Putman, Charles T.
影响因子：
3.3
作者：
Sewell, Dean A.;Robinson, Tristan M.;Greenhaff, Paul L.
通讯作者：
Greenhaff, Paul L.