The mental health of individuals referred for assessment of autism spectrum disorder in adulthood: A clinic report
The mental health of individuals referred for assessment of autism spectrum disorder in adulthood: A clinic report
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DOI：
10.1177/1362361315604271
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发表时间：
2016-07-01
期刊：
影响因子：
5.2
通讯作者：
Murphy, Declan G. M.
中科院分区：
文献类型：
--
作者：
Russell, Ailsa J.;Murphy, Clodagh M.;Murphy, Declan G. M.
人们对自闭症谱系障碍的认识不断提高，增加了对成年诊断服务的需求。据报道，患有自闭症谱系障碍的年轻人和成年人出现心理健康问题的比例很高。然而，抽样和方法学问题意味着关于自闭症谱系障碍精神共病特异性的患病率估计和结论仍不清楚。对 859 名接受自闭症谱系障碍评估的成年人进行回顾性病例审查，比较了符合自闭症谱系障碍标准的患者 (n=474) 和不符合自闭症谱系障碍标准的患者 (n=385) 的《国际疾病分类》第十版修订版诊断结果。两组的精神科诊断率（>57%）相当，并且在许多情况下超过了一般人群的诊断率。患有自闭症谱系障碍的成年人中焦虑症，特别是强迫症的患病率显着高于没有自闭症谱系障碍的成年人。这项观察性临床研究的局限性可能会影响研究结果的普遍性，包括评估者缺乏标准化的结构化精神病学诊断评估，而评估者对自闭症谱系障碍的诊断和评估者间的可靠性视而不见。这项研究的意义凸显了需要仔细考虑所有接受自闭症谱系障碍诊断的成年人的心理健康需求。
Growing awareness of autism spectrum disorders has increased the demand for diagnostic services in adulthood. High rates of mental health problems have been reported in young people and adults with autism spectrum disorder. However, sampling and methodological issues mean prevalence estimates and conclusions about specificity in psychiatric co-morbidity in autism spectrum disorder remain unclear. A retrospective case review of 859 adults referred for assessment of autism spectrum disorder compares International Classification of Diseases, Tenth Revision diagnoses in those that met criteria for autism spectrum disorder (n=474) with those that did not (n=385). Rates of psychiatric diagnosis (>57%) were equivalent across both groups and exceeded general population rates for a number of conditions. The prevalence of anxiety disorders, particularly obsessive compulsive disorder, was significantly higher in adults with autism spectrum disorder than adults without autism spectrum disorder. Limitations of this observational clinic study, which may impact generalisability of the findings, include the lack of standardised structured psychiatric diagnostic assessments by assessors blind to autism spectrum disorder diagnosis and inter-rater reliability. The implications of this study highlight the need for careful consideration of mental health needs in all adults referred for autism spectrum disorder diagnosis.