Study of retrieved acetabular sockets made from high-dose, cross-linked polyethylene.
Study of retrieved acetabular sockets made from high-dose, cross-linked polyethylene.
复制标题
研究由高剂量交联聚乙烯制成的回收髋臼窝。
DOI：
10.1054/arth.2001.28371
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发表时间：
2001
影响因子：
3.5
通讯作者：
H. Amino
中科院分区：
文献类型：
--
作者：
H. Oonishi;Ian C. Clarke;S. Masuda;H. Amino
虽然超高相对分子质量聚乙烯(UHMWPE)具有稳定的化学性质，但氧化反应等化学降解随着临床的长期应用而不断发展。本研究的目的是通过检测回收的超高相对分子质量聚乙烯(UHMWPE)插座和高剂量交联型PE(100Mrad PE)插座来研究聚乙烯(PE)在体内的性能变化。对1970~1996年间植入的20个牙槽窝(包括2100Mrad PE槽)进行分析。在磨损区，100Mrad PE插座的氧化指数与正常UHMWPE插座的氧化指数基本相同。这些长期的临床结果表明，100mrad PE足够稳定，可用于临床，自由基不会显著影响氧化进程。
Although ultra-high molecular weight polyethylene (UHMWPE) has stable chemical properties, chemical degradation, such as oxidation reaction, progresses with long-term clinical use. The purpose of this study was to investigate the change in properties of polyethylene (PE) in vivo by examining retrieved UHMWPE sockets and high-dose, cross-linked PE (100 Mrad PE) sockets. Twenty retrieved sockets (including 2 100 Mrad PE sockets), which were implanted from 1970 to 1996, were used for analysis. The oxidation index of 100 Mrad PE sockets was approximately the same as that of the normal UHMWPE sockets in worn areas. These long-term clinical results indicate that 100 Mrad PE is sufficiently stable for clinical use and that free radicals would not affect progression of oxidation significantly.