Collateral Circulation in Moyamoya Disease: A New Grading System
Collateral Circulation in Moyamoya Disease: A New Grading System
复制标题
烟雾病的侧支循环：新的分级系统
DOI：
10.1161/strokeaha.119.024487
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发表时间：
2019-10-01
期刊：
影响因子：
8.3
通讯作者：
Duan, Lian
中科院分区：
文献类型：
--
作者：
Liu, Zhi-wen;Han, Cong;Duan, Lian
背景和目的：预测脑卒中的风险和确定干预指征对烟雾病（MMD）患者非常重要。在这里，我们评估了一种新的MMD分级系统的基础上侧支循环和铃木阶段，以评估症状和预测pregnancy.Methods-In总数，301特发性MMD患者进行了回顾性分析2014年和2016年之间。建立侧支循环分级系统，评分范围为1~12分：大脑后动脉至大脑中动脉和大脑前动脉的软脑膜侧支血流解剖范围评分为1~6分;穿支侧支和大脑内动脉血流评分为6~1分，对应Suzuki 1~6级。动态磁敏感对比磁共振成像用于评估血流动力学状态。我们评估了分级系统与临床特征之间的关联。结果-我们分析了301名患者（146名男性，2816岁）的364个有症状的半球。表现为梗死的缺血性患者更容易评分
Background and Purpose-Predicting the risk of stroke and determining intervention indications are highly important for patients with Moyamoya disease (MMD). Here, we evaluated a novel MMD grading system based on collateral circulation and Suzuki stage to evaluate symptoms and predict prognosis.Methods-In total, 301 idiopathic MMD patients were retrospectively analyzed between 2014 and 2016. A collateral circulation grading system with scores ranging from 1 to 12 was established: the anatomic extent of pial collateral blood flow from posterior cerebral artery to middle cerebral artery and anterior cerebral artery was scored from 1 to 6; perforator collateral and internal cerebral artery flow were scored as 6 to 1, which corresponded to Suzuki stages 1 to 6. Dynamic susceptibility contrast-magnetic resonance imaging was used to evaluate hemodynamic status. We assessed the association between the grading system and clinical characteristics.Results-We analyzed 364 symptomatic hemispheres of 301 patients (146 males, 2816 years). Ischemic patients who presented with infarction were more likely to score