Twin-to-twin transfusion syndrome (TTTS)

Twin-to-twin transfusion syndrome (TTTS)
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DOI:
10.1515/jpm.2010.147
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发表时间:
2011-03-01
影响因子:
2.4
通讯作者:
Ville, Yves
Ville, Yves
中科院分区:
医学4区
文献类型:
--
作者:
Baschat, Ahmet;Chmait, Ramen H.;Ville, Yves

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双胎输血综合征(TTTS)是单绒毛膜(MC)双胞胎妊娠的一种严重并发症,其特征是血液通过胎盘吻合口从一个被定义为供体的双胞胎转移到另一个被定义为受体的双胞胎。如果不及时治疗,由于胎儿和/或产科并发症,TTTS与非常高的围产期死亡率和发病率有关。据报道,所有MC双胞胎的患病率为10-15%,或约2000例妊娠中有1例。这份共识文件回顾了现有的证据,并通过提供有关TTTS诊断和管理的各个方面的建议,为临床医生提供了实用的指导。
Twin-to-twin transfusion syndrome (TTTS) is a severe complication of monochorionic (MC) twin pregnancies, characterized by the development of unbalanced chronic blood transfer from one twin, defined as donor twin, to the other, defined as recipient, through placental anastomoses. If left untreated, TTTS is associated with very high perinatal mortality and morbidity rates, due to a combination of fetal and/or obstetric complications. The reported prevalence is 10-15% of all MC twins, or about 1 in 2000 pregnancies. This consensus document reviews available evidence and offers practical guidance to clinicians by providing recommendations on various aspects concerning diagnosis and management of TTTS.