DEFICITS IN PSYCHOLOGIC AND CLASSROOM PERFORMANCE OF CHILDREN WITH ELEVATED DENTIN LEAD LEVELS
DEFICITS IN PSYCHOLOGIC AND CLASSROOM PERFORMANCE OF CHILDREN WITH ELEVATED DENTIN LEAD LEVELS
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DOI：
10.1056/nejm197903293001301
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发表时间：
1979-01-01
影响因子：
158.5
通讯作者：
BARRETT, P
中科院分区：
文献类型：
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作者：
NEEDLEMAN, HL;GUNNOE, C;BARRETT, P
为了测量不明原因的儿童铅暴露对神经心理的影响，对58名牙本质铅水平高的儿童和100名牙本质铅水平低的儿童的表现进行了比较。高铅儿童在韦氏儿童智力量表(修订本)上的得分显著低于低铅儿童。这种差异在言语测试、听觉或语音处理的其他3项指标以及注意力的一项指标上也很明显。方差分析表明，所有这些差异都不能用所研究的39个其他变量中的任何一个来解释。通过教师问卷对2146名儿童的课堂行为进行了评估，并对他们的牙齿进行了分析。非适应性课堂行为的频率随着牙本质铅水平的增加而增加。铅暴露的剂量低于那些产生严重到足以被临床诊断的症状的剂量，似乎与神经心理缺陷有关，这可能会干扰课堂表现。
To measure the neuropsychological effects of unidentified childhood exposure to Pb, the performance of 58 children with high and 100 with low dentine Pb levels was compared. Children with high Pb levels scored significantly lower on the Wechsler Intelligence Scale for Children (Revised) than those with low Pb levels. This difference was also apparent on verbal subtests, on 3 other measures of auditory or speech processing and on a measure of attention. Analysis of variance showed that none of these differences could be explained by any of the 39 other variables studied. Also evaluated by a teachers'' questionnaire was the classroom behavior of all children (2146) whose teeth were analyzed. The frequency of non-adaptive classroom behavior increased in a dose-related fashion to dentine Pb level. Pb exposure, at doses below those producing symptoms severe enough to be diagnosed clinically, appears to be associated with neuropsychological deficits that may interfere with classroom performance.