Continuous intravenous infusion of ampicillin and gentamicin during parenteral nutrition in 88 newborn infants.
Continuous intravenous infusion of ampicillin and gentamicin during parenteral nutrition in 88 newborn infants.
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88例新生儿肠外营养期间持续静脉滴注氨苄青霉素和庆大霉素。
DOI：
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发表时间：
1982
影响因子：
5.2
通讯作者：
G. E. Andersen
中科院分区：
文献类型：
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作者：
H. Colding;S. Møller;G. E. Andersen
将氨苄青霉素和庆大霉素溶于专门为新生儿肠外营养制备的L-氨基酸溶液中，每天一次，并连续输注给88名怀疑或已证实败血症的婴儿。平均剂量分别为162和5.3 mg/kg/24小时，血清浓度的95%限度分别为11-133和1.3-7.4 μ g/ml。治疗结果至少与间歇性肌内或静脉给药一样好。这种新的抗生素给药模式对婴儿的痛苦较小，对护士来说也更容易。
Ampicillin and gentamicin were dissolved once a day in an L-amino acid solution especially prepared for parenteral nutrition of newborn infants and infused continuously to 88 infants in whom septicaemia was suspected or had been proved. The mean dosages were 162 and 5.3 mg/kg per 24 hours respectively, and the 95% limits for the serum concentrations were 11-133 and 1.3-7.4 micrograms/ml. The treatment results were at least as good as with intermittent intramuscular or intravenous administration. This new mode of giving antibiotics is less painful to the babies and easier for the nurses.