Three syntheses of trans-cyclooctane-1,2-dithiol by ring opening of cis-cyclooctene episulfoxide with ammonium thiocyanate followed by reduction and reductions of trans-1,2-di(thiocyanato)cyclooctane and trans-1,2-cyclooctyl trithiocarbonate
Three syntheses of trans-cyclooctane-1,2-dithiol by ring opening of cis-cyclooctene episulfoxide with ammonium thiocyanate followed by reduction and reductions of trans-1,2-di(thiocyanato)cyclooctane and trans-1,2-cyclooctyl trithiocarbonate
复制标题
顺式环辛烯环亚砜与硫氰酸铵开环，再还原反式1,2-二(氰硫基)环辛烷和反式1,2-环辛基三硫代碳酸酯，三次合成反式环辛烷-1,2-二硫醇
DOI：
10.1080/17415990902839435
复制
发表时间：
2009
影响因子：
2.2
通讯作者：
N. Nakata
中科院分区：
文献类型：
--
作者：
A. Ishii;Ayako Ono;N. Nakata
采用三种方法合成反式环辛烷-1,2-二硫醇：(1)用NH4SCN在四氢呋喃中开环，然后用二异丁基铝氢化物（DIBAH）在己烷中逐步还原，再用LiAlH4在乙醚中还原；（ii）用DIBAH和LiAlH4逐步还原反式-1,2-二（硫氰酸酯）环辛烷11；（iii）用LiAlH4在回流醚中还原反式-1,2-环辛基三硫代碳酸盐。详细考察了方法(1)的反应过程。
trans-Cyclooctane-1,2-dithiol was synthesized by three methods: (i) ring opening of trans-cyclooctene episulfoxide with NH4SCN in THF followed by a stepwise reduction with diisobutylaluminum hydride (DIBAH) in hexane and then LiAlH4 in ether; (ii) a stepwise reduction of trans-1,2-di(thiocyanato)cyclooctane 11 with DIBAH and then LiAlH4; and (iii) the reduction of trans-1,2-cyclooctyl trithiocarbonate with LiAlH4 in refluxing ether. The course of reactions of method (i) was investigated in detail.
影响因子：
15
作者：
J. Nakayama;Y. Tajima;Pi Xue-hua;Y. Sugihara
通讯作者：
J. Nakayama;Y. Tajima;Pi Xue-hua;Y. Sugihara