WikiPathways: capturing the full diversity of pathway knowledge.

WikiPathways: capturing the full diversity of pathway knowledge.
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DOI:
10.1093/nar/gkv1024
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发表时间:
2016-01-04
影响因子:
14.9
通讯作者:
Pico AR
Pico AR
中科院分区:
生物学2区
文献类型:
--
作者:
Kutmon M;Riutta A;Nunes N;Hanspers K;Willighagen EL;Bohler A;Mélius J;Waagmeester A;Sinha SR;Miller R;Coort SL;Cirillo E;Smeets B;Evelo CT;Pico AR

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WikiPathways(www.wikipathways.org)是一个开放的协作平台,用于捕获和传播生物学途径模型,以进行数据可视化和分析。自4年前的NAR更新以来,WikiPathways经历了内容的大规模增长,每年仍有数百人贡献内容。新的方面的多样性和深度的收集途径的研究人员有兴趣在他们的研究中使用的途径信息的角度进行描述。我们提供扩展和服务的更新,以支持通过流行的独立工具,即Pathscope和Cytoscape,Web应用程序和常见的编程环境进行途径分析和可视化。我们为路径作者和策展人介绍了快速编辑功能,以及发布路径和维护自定义路径集合的新方法,以服务于特定的研究主题和社区。除了在我们的路径收集和策展工作的最新里程碑,我们还强调了最新的手段来访问内容作为可扩展的数字,作为标准数据文件,并作为链接的数据,包括批量和编程访问。
WikiPathways (http://www.wikipathways.org) is an open, collaborative platform for capturing and disseminating models of biological pathways for data visualization and analysis. Since our last NAR update, 4 years ago, WikiPathways has experienced massive growth in content, which continues to be contributed by hundreds of individuals each year. New aspects of the diversity and depth of the collected pathways are described from the perspective of researchers interested in using pathway information in their studies. We provide updates on extensions and services to support pathway analysis and visualization via popular standalone tools, i.e. PathVisio and Cytoscape, web applications and common programming environments. We introduce the Quick Edit feature for pathway authors and curators, in addition to new means of publishing pathways and maintaining custom pathway collections to serve specific research topics and communities. In addition to the latest milestones in our pathway collection and curation effort, we also highlight the latest means to access the content as publishable figures, as standard data files, and as linked data, including bulk and programmatic access.