In vivo quantification of the shear modulus of the human Achilles tendon during passive loading using shear wave dispersion analysis
In vivo quantification of the shear modulus of the human Achilles tendon during passive loading using shear wave dispersion analysis
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DOI：
10.1088/0031-9155/61/6/2485
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发表时间：
2016-03-21
影响因子：
3.5
通讯作者：
Gennisson, J-L
中科院分区：
文献类型：
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作者：
Helfenstein-Didier, C.;Andrade, R. J.;Gennisson, J-L
用相速度法分析被动背屈时跟腱(AT)的剪切波速频散，得到跟腱剪切模数(C-55)。基于这一分析，本研究的目的是(I)评估不同踝关节角度的剪切模数的重复性，(Ii)评估探头位置的影响，以及(Iii)将结果与超声剪切成像(SSI)技术获得的弹性值进行比较。随着踝关节背屈(N=10，p<；0.05)，AT剪切模数(C-55)持续增加。此外，该技术显示出很好的重复性(平均值的所有标准误差和所有变异系数(CV)值均为10.7kPa)。0.05%)。此外，独立于踝关节背屈，近端位置的剪切模数显著高于远端位置。SSI提供的剪切模量值始终低于C55，且随着踝关节背屈的增加，其差值增大。然而，两种方法提供的剪切模量值高度相关(R=0.84)，这表明传统的剪切波弹性成像技术(SSI技术)可以用于比较不同人群的肌腱力学性能。未来的研究应该确定剪切波离散度分析的临床相关性，例如在肌腱病变或肌腱撕裂的情况下。
The shear wave velocity dispersion was analyzed in the Achilles tendon (AT) during passive dorsiflexion using a phase velocity method in order to obtain the tendon shear modulus (C-55). Based on this analysis, the aims of the present study were (i) to assess the reproducibility of the shear modulus for different ankle angles, (ii) to assess the effect of the probe locations, and (iii) to compare results with elasticity values obtained with the supersonic shear imaging (SSI) technique. The AT shear modulus (C-55) consistently increased with the ankle dorsiflexion (N = 10, p < 0.05). Furthermore, the technique showed a very good reproducibility (all standard error of the mean values < 10.7 kPa and all coefficient of variation (CV) values. 0.05%). In addition, independently from the ankle dorsiflexion, the shear modulus was significantly higher in the proximal location compared to the more distal one. The shear modulus provided by SSI was always lower than C55 and the difference increased with the ankle dorsiflexion. However, shear modulus values provided by both methods were highly correlated (R = 0.84), indicating that the conventional shear wave elastography technique (SSI technique) can be used to compare tendon mechanical properties across populations. Future studies should determine the clinical relevance of the shear wave dispersion analysis, for instance in the case of tendinopathy or tendon tear.