Endometrial and subendometrial perfusion are impaired in women with unexplained subfertility
Endometrial and subendometrial perfusion are impaired in women with unexplained subfertility
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DOI：
10.1093/humrep/deh459
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发表时间：
2004-11-01
影响因子：
6.1
通讯作者：
Johnson, IR
中科院分区：
文献类型：
--
作者：
Raine-Fenning, NJ;Campbell, BK;Johnson, IR
背景：我们使用三维能量多普勒血管造影 (3D-PDA) 检查 29 名不明原因生育力低下的女性和 19 名对照者在正常月经周期期间子宫内膜发育和子宫内膜下血管分布的周期性变化。方法：从周期第 3 天直至排卵，每隔一天进行 3D-PDA，然后每 4 天进行一次，直至月经来潮。 VOCAL(TM)（虚拟器官计算机辅助分析）和壳成像用于定义和量化子宫内膜和子宫内膜下区域内的功率多普勒信号，产生其相对血管分布的指数。结果：患有不明原因不孕症的女性随着时间的推移表现出显着的变化（P
Background: We used three-dimensional power Doppler angiography (3D-PDA) to examine the periodic changes in endometrial development and subendometrial vascularity during the normal menstrual cycle in 29 women with unexplained subfertility and 19 controls. Methods: 3D-PDA was performed on alternate days from day 3 of the cycle until ovulation and then every 4 days until menses. VOCAL(TM) (Virtual Organ Computer-aided AnaLysis) and shell-imaging were used to define and to quantify the power Doppler signal within the endometrial and subendometrial regions producing indices of their relative vascularity. Results: Women with unexplained subfertility demonstrated significant changes with time (P