Severe hypocalcemia following a single injection of denosumab in a patient with renal impairment.
Severe hypocalcemia following a single injection of denosumab in a patient with renal impairment.
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DOI：
10.3109/21556660.2012.668504
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发表时间：
2012
影响因子：
2.4
通讯作者：
Talreja DB
中科院分区：
文献类型：
--
作者：
Talreja DB
Denosumab（60 mg，每6个月一次）不需要监测肾功能和调整肾功能受损患者的剂量。然而，这些患者发生低钙血症的风险增加。本病例报告描述了1例肾损害患者，该患者在接受Denosumab治疗后发生重度低钙血症。
Monitoring renal function and adjusting dosing for patients with impaired renal function are not required with denosumab (60 mg every 6 months). However, these patients have an increased risk for developing hypocalcemia. This case report describes a patient with renal impairment who developed severe hypocalcemia after receiving denosumab.