The "fit but fat" paradigm addressed using accelerometer-determined physical activity data.
The "fit but fat" paradigm addressed using accelerometer-determined physical activity data.
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DOI：
10.4103/1947-2714.136901
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发表时间：
2014-07
期刊：
影响因子：
--
通讯作者：
Blair SN
中科院分区：
文献类型：
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作者：
Loprinzi P;Smit E;Lee H;Crespo C;Andersen R;Blair SN
没有研究使用加速度测量数据来解决“健康但肥胖”的范式。该研究旨在确定：1）更高水平的加速度计确定的身体活动是否与超重或肥胖者的生物标志物有利相关（目标1）;以及2）足够活跃的超重或肥胖个体是否比活动不足的正常体重者具有更好或相似的生物标志物水平（目标2）。对2003-2006年全国健康和营养检查调查的数据进行了分析，其中包括5,146名年龄在20-85岁之间的参与者。关于目标1，与肥胖的非活动个体相比，肥胖的活动个体具有更有利的腰围、C反应蛋白、白色血细胞和中性粒细胞水平;超重成人也发现了类似的结果。关于目标2，正常体重非活动个体和超重活动个体之间几乎所有生物标志物均无显著差异。同样，正常体重不活动的人和肥胖活动的人之间的白色血细胞、中性粒细胞、低密度脂蛋白胆固醇、总胆固醇、甘油三酯、葡萄糖或同型半胱氨酸也没有显著差异。体力活动对正常、超重和肥胖个体的生物标志物具有保护作用，并且超重（非肥胖）活动个体具有与正常体重非活动个体相似的心血管特征。
No studies have addressed the “fit but fat” paradigm using accelerometry data. The study was to determine if 1) higher levels of accelerometer-determined physical activity are favorably associated with biomarkers in overweight or obese persons (objective 1); and 2) overweight or obese individuals who are sufficiently active have better or similar biomarker levels than normal weight persons who are not sufficiently active (objective 2). Data from the 2003-2006 National Health and Nutrition Examination Survey were analyzed and included 5,146 participants aged 20-85 years. Regarding objective 1, obese active individuals had more favorable waist circumference, C-reactive protein, white blood cells, and neutrophil levels when compared to obese inactive individuals; similar results were found for overweight adults. Regarding objective 2, there were no significant differences between normal weight inactive individuals and overweight active individuals for nearly all biomarkers. Similarly, there were no significant differences between normal weight inactive individuals and obese active individuals for white blood cells, neutrophils, low-density lipoprotein cholesterol, total cholesterol, triglycerides, glucose, or homocysteine. Physical activity has a protective effect on biomarkers in normal, overweight, and obese individuals, and overweight (not obese) active individuals have a similar cardiovascular profile than normal weight inactive individuals.