Disorders of agency in schizophrenia correlate with an inability to compensate for the sensory consequences of actions
Disorders of agency in schizophrenia correlate with an inability to compensate for the sensory consequences of actions
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DOI：
10.1016/j.cub.2005.05.049
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发表时间：
2005-06-21
期刊：
影响因子：
9.2
通讯作者：
Leube, DT
中科院分区：
文献类型：
--
作者：
Lindner, A;Thier, P;Leube, DT
精神分裂症患者的精神病理症状表明，这些人的自我概念可能受到干扰[1]。影响力的错觉让他们觉得别人在指导他们的行动，他们的某些类型的幻觉似乎是对自己内心的声音作为外部声音的误解，共同的特点是，自己产生的信息被认为是来自外部的。如果这种解释是正确的，我们可能会认为，精神分裂症患者可能还会将自己眼球运动的感觉后果归因于环境，而不是自己，挑战稳定世界的感知。事实上，情况似乎就是这样，因为我们发现影响妄想的强度与精神分裂症患者在运动感知中抵消这种自我诱导的视网膜信息的能力之间存在明显的相关性。这种相关性反映了支持这一观点的直接实验证据，即精神分裂症中的影响妄想可能是由于对自己行为的感觉后果的感知补偿的特定缺陷[1-6]。
Psychopathological symptoms in schizophrenia patients suggest that the concept of self might be disturbed in these individuals [1]. Delusions of influence make them feel that someone else is guiding their actions, and certain kinds of their hallucinations seem to be misinterpretations of their own inner voice as an external voice, the common denominator being that self-produced information is perceived as if coming from outside. If this interpretation were correct, we might expect that schizophrenia patients might also attribute the sensory consequences of their own eye movements to the environment rather than to themselves, challenging the percept of a stable world. Indeed, this seems to be the case because we found a clear correlation between the strength of delusions of influence and the ability of schizophrenia patients to cancel out such self-induced retinal information in motion perception. This correlation reflects direct experimental evidence supporting the view that delusions of influence in schizophrenia might be due to a specific deficit in the perceptual compensation of the sensory consequences of one's own actions [1-6].