Exploring and engineering the cell surface interface.
Exploring and engineering the cell surface interface.
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DOI：
10.1016/j.bpj.2010.12.1248
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发表时间：
2011-02
期刊：
影响因子：
56.9
通讯作者：
M. Stevens;Julian H. George
中科院分区：
文献类型：
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作者：
M. Stevens;Julian H. George
本演讲将概述我们在用于细胞反应和组织再生的仿生纳米材料方面的最新进展 (1, 2)。组织工程这个高度跨学科的领域可以极大地受益于生物响应纳米材料设计的进步。 TE 涉及人工支架结构的开发，以促进新细胞在其上生长。在纳米尺度上控制形貌和化学的能力为通过开发模拟体内组织纳米结构的新型纳米结构支架来刺激新组织的生长提供了令人兴奋的可能性。将讨论这方面的最新进展以及使用活细胞拉曼显微光谱监测细胞和组织发育的新方法 (3)。
This talk will provide an overview of our recent developments in bio-inspired nanomaterials for cell response and tissue regeneration (1, 2). The highly interdisciplinary field of Tissue Engineering can greatly benefit from advances in the design of bio-responsive nanomaterials. TE involves the development of artificial scaffold structures on which new cells are encouraged to grow. The ability to control topography and chemistry at the nanoscale offers exciting possibilities for stimulating growth of new tissue through the development of novel nanostructured scaffolds that mimic the nanostructure of the tissues in the body. Recent developments in this context will be discussed as well as novel approaches to monitor cell and tissue development using live cell Raman microspectroscopy (3).