Psychosis in a 12-year-old HIV-positive girl with an increased serum concentration of efavirenz.
Psychosis in a 12-year-old HIV-positive girl with an increased serum concentration of efavirenz.
复制标题
一名 12 岁 HIV 阳性女孩因依非韦伦血清浓度升高而出现精神病。
DOI：
10.1086/522764
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
D. Pugatch
中科院分区：
文献类型：
--
作者：
Elizabeth A. Lowenhaupt;K. Matson;B. Qureishi;A. Saitoh;D. Pugatch
Clearance and adverse effects of efavirenz are associated with CYP2B6-G516T polymorphism. Little is known about the prevalence of genotypes and implications for screening in children. We report (to our knowledge, for the first time in a child) the emergence of psychosis in a 12-year old white girl with an increased efavirenz concentration and heterozygous gene polymorphism of the CYP2B6-G516T.
影响因子：
6.4
作者：
Haas, DW;Smeaton, LM;Kim, RB
通讯作者：
Kim, RB