BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types
BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types
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DOI：
10.1093/nar/gku1244
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发表时间：
2015-01-28
影响因子：
14.9
通讯作者：
Clemons, P. A.
中科院分区：
文献类型：
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作者：
Howe, E. A.;de Souza, A.;Clemons, P. A.
BARD，生物测定研究数据库（https：//bard.nih.gov/）是一个公共数据库和一套工具，旨在提供对NIH分子图书馆计划（MLP）产生的生物测定数据的访问。来自631个MLP项目的数据被迁移到一个新的结构化词汇表中，该词汇表旨在以正式的方式捕获生物测定数据，特别强调对测定方案的描述。新数据可以通过一组用户友好的工具提交给BARD，这些工具有助于创建适当格式的数据集和测定定义。通过BARD应用程序接口（API）发布的数据可以由研究人员使用基于Web的查询工具或桌面客户端访问。希望创建新工具的第三方开发人员可以使用API来生成可以集成到BARD中的独立工具或新插件。因此，整个BARD工具套件支持三类研究人员：那些希望发布数据的人，那些希望为可测试的假设挖掘数据的人，以及那些希望构建利用这种精心策划的化学生物学资源的工具的开发人员社区。
BARD, the BioAssay Research Database (https://bard.nih.gov/) is a public database and suite of tools developed to provide access to bioassay data produced by the NIH Molecular Libraries Program (MLP). Data from 631 MLP projects were migrated to a new structured vocabulary designed to capture bioassay data in a formalized manner, with particular emphasis placed on the description of assay protocols. New data can be submitted to BARD with a user-friendly set of tools that assist in the creation of appropriately formatted datasets and assay definitions. Data published through the BARD application program interface (API) can be accessed by researchers using web-based query tools or a desktop client. Third-party developers wishing to create new tools can use the API to produce stand-alone tools or new plug-ins that can be integrated into BARD. The entire BARD suite of tools therefore supports three classes of researcher: those who wish to publish data, those who wish to mine data for testable hypotheses, and those in the developer community who wish to build tools that leverage this carefully curated chemical biology resource.