The Comorbidity of Diabetes Mellitus and Depression
The Comorbidity of Diabetes Mellitus and Depression
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DOI：
10.1016/j.amjmed.2008.09.008
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发表时间：
2008-11-01
影响因子：
5.9
通讯作者：
Katon, Wayne J.
中科院分区：
文献类型：
--
作者：
Katon, Wayne J.
包括久坐不动的生活方式、肥胖和人口老龄化在内的几个因素导致了2型糖尿病的流行。抑郁症经常与糖尿病并存，尽管在这两种疾病的患者中，大约三分之二的人没有意识到抑郁症，也没有得到治疗。同时患有糖尿病和抑郁症的患者的抑郁病程是慢性的和严重的。高达80%的糖尿病和抑郁症患者将在5年内经历抑郁症状的复发。抑郁症与不坚持糖尿病自我护理有关--包括遵循饮食限制、服药依从性和血糖监测--导致整体临床结果更差。由于与糖尿病和抑郁症共病相关的潜在的负面健康后果，这两种情况都应该得到最佳的治疗，以最大化患者的预后。(C)2008 Elsevier Inc.保留所有权利。《美国医学杂志》(2008)121，S8-S15
Several factors, including sedentary lifestyle, obesity, and an aging population, contribute to epidemic rates of type 2 diabetes mellitus. Depression frequently occurs comorbidly with diabetes although it is unrecognized and untreated in approximately two thirds of patients with both conditions. The course of depression in patients with both diabetes and depression is chronic and severe. Up to 80% of patients with diabetes and depression will experience a relapse of depressive symptoms over a 5-year period. Depression is associated with nonadherence to diabetes self-care - including following dietary restrictions, medication compliance, and blood glucose monitoring - resulting in worse overall clinical outcomes. Due to potential negative health consequences associated with comorbid diabetes and depression, both conditions should be optimally treated to maximize patient outcomes. (C) 2008 Elsevier Inc. All rights reserved. The American Journal of Medicine (2008) 121, S8-S15