N-Heterocyclic Carbene Derived Nickel-Pincer Complexes: Efficient and Applicable Catalysts for Suzuki-Miyaura Coupling Reactions of Aryl/Alkenyl Tosylates and Mesylates
N-Heterocyclic Carbene Derived Nickel-Pincer Complexes: Efficient and Applicable Catalysts for Suzuki-Miyaura Coupling Reactions of Aryl/Alkenyl Tosylates and Mesylates
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DOI：
10.1002/ejoc.200900067
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发表时间：
2009-05-01
影响因子：
2.8
通讯作者：
Doi, Takayuki
中科院分区：
文献类型：
--
作者：
Kuroda, Jun-ichi;Inamoto, Kiyofumi;Doi, Takayuki
研究了NHC衍生的镍钳形配合物对芳基/烯基对甲苯磺酸酯和甲磺酸酯的Suzuki-Miyaura偶联反应的催化活性。在催化量的镍镧1a的存在下，广泛的甲苯磺酸酯和甲磺酸酯与几种芳基硼酸和烯基硼酸反应，通常以高产率得到偶联产物。只有通过选择适当的反应介质（DME用于甲苯磺酸酯，二氧六环用于甲磺酸酯），才能对每类亲电试剂的反应条件进行微调。((c)Wiley-VCH Verlag GmbH & Co. KGaA，69451魏因海姆，德国，2009）
Catalytic activities of NHC-derived nickel-pincer complexes for the Suzuki-Miyaura coupling reactions of aryl/alkenyl to-sylates and mesylates are described. In the presence of a catalytic amount of nickelacycle 1a, a wide array of tosylates and mesylates reacted with several aryl- and alkenylboronic acids to afford the coupling products, generally in high yields. Fine tuning of the reaction conditions for each class of electrophiles was achieved only by choosing the appropriate reaction medium (DME for tosylates, dioxane for mesylates). ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)