Genomic evolution, host-species barrier, reassortment and classification of rotaviruses

Genomic evolution, host-species barrier, reassortment and classification of rotaviruses
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轮状病毒的基因组进化、宿主物种屏障、重配和分类

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发表时间:
2010
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通讯作者:
M. Ranst
M. Ranst
中科院分区:
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作者:
J. Matthijnssens;V. Martella;M. Ranst

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评价:Yamamoto D、Ghosh S、Ganesh B等人:基于全基因组片段的人B组轮状病毒遗传多样性和分子进化分析。J.将军·维罗尔91(Pt 7),1772-1781(2010)。轮状病毒是呼肠孤病毒科的成员,在人类和动物中引起严重的腹泻和死亡。它们被细分为至少七个血清学组(A-G),最近发现了一种新的轮状病毒,称为“新成人腹泻病毒”或ADRV-N。只有在A组轮状病毒中,才有大量的毒株在分子水平上得到了完全的分析。对于B、C和ADRV-N组轮状病毒,可获得的完整基因组数量非常有限,而对于D、E和F组,完全没有序列数据。在这里,Yamamoto及其同事描述了在印度、孟加拉国和缅甸分离的四种人类B组轮状病毒的全基因组特征。对这4个菌株进行了遗传学分析,并将单个基因片段与它们的基因片段进行了比较。
Evaluation of: Yamamoto D, Ghosh S, Ganesh B et al.: Analysis on genetic diversity and molecular evolution of human group B rotaviruses based on whole genome segments. J. Gen. Virol. 91(Pt 7), 1772–1781 (2010). Rotaviruses are members of the Reoviridae family, causing severe diarrheal illness and death in humans and animals. They have been subdivided into at least seven serological groups (A–G), and, recently, a new rotavirus known as ‘new adult diarrhea virus’ or ADRV-N was discovered. Only in group A rotaviruses have a substantial number of strains been analyzed completely on the molecular level. For groups B, C and ADRV-N rotaviruses a very limited number of complete genomes are available, and for group D, E and F no sequence data are available at all. Here, Yamamoto and colleagues describe the full genomic characterization of four human group B rotaviruses isolated in India, Bangladesh and Myanmar. These four strains were analyzed phylogenetically and individual gene segments were compared with their ...