Range-modulated pencil beam algorithm for proton dose calculations
Range-modulated pencil beam algorithm for proton dose calculations
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DOI：
10.1143/jjap.40.5187
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发表时间：
2001-08-01
期刊：
影响因子：
--
通讯作者：
Matsuda, H
中科院分区：
文献类型：
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作者：
Kohno, R;Takada, Y;Matsuda, H
在铅笔束算法的基础上，提出了一种范围调制铅笔束算法（RMPBA）用于质子治疗规划，以减少计算时间，同时达到足够的精度。它使用距离调制光束的深度剂量分布作为铅笔光束的中心轴项。距离调制铅笔束的传播是通过假设质子通过脊状滤光器的平均厚度推导出来的。通过与硅半导体探测器在水中进行的剂量测量进行比较，验证了RMPBA剂量计算的准确性。测量的剂量分布结果与RMPBA计算的结果吻合较好。RMPBA所需的计算时间是PBA所需计算时间的六分之一，在六步脊式滤波器的情况下。因此，RMPBA的剂量计算方法对质子治疗的实际治疗计划是有用的和适用的。
The range-modulated pencil beam algorithm (RMPBA) has been developed for proton treatment planning on the basis of the pencil beam algorithm (PBA) to reduce the calculation time yet realize sufficient accuracy. It uses the depth-dose distribution of the range-modulated beam as a central-axis term of pencil beams. The spread of the range-modulated pencil beam is derived by assuming that the protons pass through the average thickness of the ridge-filter. The accuracy of dose calculations by the RMPBA is verified by comparison with dose measurements in water performed using a silicon semiconductor detector. The results of the measured dose distributions agree well with those of the calculations using the RMPBA, Furthermore. the calculation time required by the RMPBA is one-sixth of that required by the PBA in the case of the six-step ridge-filter. Therefore, the dose-calculation method by the RMPBA will be useful and applicable to actual treatment planning of proton therapy.