Protein expression pattern distinguishes different lymphoid neoplasms
Protein expression pattern distinguishes different lymphoid neoplasms
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DOI：
10.1002/pmic.200401286
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发表时间：
2005-11-01
期刊：
影响因子：
3.4
通讯作者：
Hirohashi, S
中科院分区：
文献类型：
--
作者：
Fujii, K;Kondo, T;Hirohashi, S
为了鉴定与淋巴样肿瘤组织学亚型相关的蛋白质，我们研究了来自人类淋巴样肿瘤的42个细胞系的蛋白质组学，包括霍奇金淋巴瘤（HL； 4个细胞系）、B细胞恶性肿瘤（19个细胞系）、T细胞恶性肿瘤（16个细胞系）和自然杀伤（NK）细胞淋巴瘤（3个细胞系）。通过(i) Wilcoxon或Kruskal-Wallis试验依次选择蛋白斑点，寻找强度显著(P
To identify proteins associated with the histological subtypes of lymphoid neoplasms, we studied the proteomes of 42 cell lines from human lymphoid neoplasms including Hodgkin's lymphoma (HL; four cell lines), B cell malignancies (19 cell lines), T cell malignancies (16 cell lines), and natural killer (NK) cell lymphoma (three cell lines). The protein spots were sequentially selected by (i) Wilcoxon or Kruskal-Wallis tests to find the spots whose intensity was significantly (P