History, haldanes and health inequities: exploring phenotypic changes in body size by generation and income level in the US-born White and Black non-Hispanic populations 1959-1962 to 2005-2008.
History, haldanes and health inequities: exploring phenotypic changes in body size by generation and income level in the US-born White and Black non-Hispanic populations 1959-1962 to 2005-2008.
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历史、haldanes 和健康不平等：探索 1959-1962 年至 2005-2008 年美国出生的白人和黑人非西班牙裔人口中不同代际和收入水平的体型表型变化。
DOI：
10.1093/ije/dys206
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发表时间：
2013
影响因子：
7.7
通讯作者：
Beckfield,Jason
中科院分区：
文献类型：
--
作者：
Krieger,Nancy;Chen,JarvisT;Waterman,PamelaD;Kosheleva,Anna;Beckfield,Jason
背景大多数关于人口健康和健康不公平趋势的公共卫生文献都涉及每年或十年观察到的或有针对性的变化率或比例。我们探索，在新的分析，是否可以获得额外的洞察力，通过使用“haldane”，一个度量标准开发的进化生物学家来衡量每一代的标准差性状的变化，从而使有意义的比较跨物种和时间periodsMethodsWe分析了身体高度的表型体现性状，美国出生的白色和黑人非西班牙裔成年人的体重和身体质量指数，年龄在20至44岁之间，在1959-1962年国家健康检查调查I至2005年期间的6个大型全国代表性人口样本中进行测量，2008年全国健康和营养调查。以前者为基线，我们计算了halalone为每个种族/民族群体的每个调查，整体和分层的家庭收入quintile.ResultsFor高度，高速率的表型变化（halalone ≥ 0.3）主要发生在1960年和1980年之间，特别是黑人人口在较高收入的五分之一。相比之下，对于体重，白色和黑色群体的高表型变化率在20世纪80年代后期变得明显，此后增加;对于身体质量指数，两组在20世纪90年代后期开始向高变化率转变，特别是在中等收入的五分之一。结论我们的研究结果支持使用的halcycle作为一个补充指标，把人口健康和健康的变化在更大的生物和历史背景下的不平等。
BackgroundMost public health literature on trends in population health and health inequities pertains to observed or targeted changes in rates or proportions per year or decade. We explore, in novel analyses, whether additional insight can be gained by using the ‘haldane’, a metric developed by evolutionary biologists to measure change in traits in standard deviations per generation, thereby enabling meaningful comparisons across species and time periods.MethodsWe analysed the phenotypic embodied traits of body height, weight and body mass index of US-born White and Black non-Hispanic adults ages 20 to 44 as measured in six large nationally representative population samples spanning from the 1959–1962 National Health Examination Survey I to the 2005–2008 National Health and Nutrition Examination Survey. Setting the former as baseline, we computed the haldane for each outcome for each racial/ethnic group for each survey, overall and stratified by family income quintile.ResultsFor height, high rates of phenotypic change (haldane ≥ 0.3) occurred chiefly between 1960 and 1980, especially for the Black population in the higher income quintiles. By contrast, for weight, high rates of phenotypic change became evident for both the White and Black populations in the late 1980s and increased thereafter; for body mass index, the shift to high rates of change started in both groups in the late 1990s, especially in the middle income quintiles.ConclusionsOur results support use of the haldane as a supplemental metric to place changes in population health and health inequities in a larger biological and historical context.