Crohn’s disease associated with renal amyloidosis successfully treated with an elemental diet

Crohn’s disease associated with renal amyloidosis successfully treated with an elemental diet
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与肾淀粉样变性相关的克罗恩病通过基本饮食成功治疗

DOI:
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发表时间:
1997
影响因子:
6.3
通讯作者:
T. Ebina
T. Ebina
中科院分区:
医学1区
文献类型:
--
作者:
Y. Horie;M. Chiba;K. Miura;M. Iizuka;O. Masamune;A. Komatsuda;T. Ebina

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我们报告一例克罗恩病肾病综合征由于肾淀粉样变性在一个21岁的男子,其中缓解克罗恩病和肾病综合征一直保持与元素的饮食。患者因肾淀粉样变性发生中毒性巨结肠和肾病综合征。强化静脉注射泼尼松龙治疗与全肠外营养是显着有效的治疗中毒性巨结肠和诱导缓解克罗恩病,随后,缓解肾病综合征。这两种情况的缓解已经维持了2年多的元素饮食。据我们所知,这是首例确诊的克罗恩病合并肾淀粉样变性病例,长期服用元素饮食仅出现轻微蛋白尿(低于0.3克/天)。
We report a case of Crohn’s disease associated with nephrotic syndrome due to renal amyloidosis in a 21-year-old man in whom remission of both Crohn’s disease and the nephrotic syndrome has been maintained with an elemental diet. The patient developed toxic megacolon and nephrotic syndrome due to renal amyloidosis. Intensive intravenous prednisolone therapy with total parenteral nutrition was dramatically effective in treating the toxic megacolon and inducing remission in Crohn’s disease and afterward, remission of the nephrotic syndrome. Remission of both conditions has been maintained for more than 2 years with the elemental diet. To our knowledge, this is the first confirmed case of Crohn’s disease complicated with renal amyloidosis in which only slight proteinuria (below 0.3 g/day) was shown with an elemental diet used for a long period.
用补充的极低蛋白质饮食治疗成人肾病。
DOI: 10.1016/s0272-6386(96)90492-8
发表时间: 1996
期刊: American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子: --
作者:
Walser,M;Hill,S;Tomalis,EA
通讯作者: Tomalis,EA