Projections of androgen-accumulating neurons in a nucleus controlling avian song.
Projections of androgen-accumulating neurons in a nucleus controlling avian song.
复制标题
控制鸟类鸣叫的细胞核中雄激素积累神经元的投射。
DOI：
10.1016/0006-8993(89)90715-4
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发表时间：
1989
期刊：
影响因子：
2.9
通讯作者：
Nordeen,EJ
中科院分区：
文献类型：
--
作者：
Sohrabji,F;Nordeen,KW;Nordeen,EJ
在斑胸草雀中，雄激素刺激鸣唱的产生并促进控制鸣唱的神经区域的生长。早期暴露于雌激素建立这种敏感性，雄激素和增加雄激素积累细胞的数量在两个歌曲区域，上纹状体腹侧部尾部（HVc）和前新纹状体。为了研究雄激素积累的这些区域变化是否会直接影响歌曲系统其他地方的雄激素反应，我们结合放射自显影和逆行追踪技术来确定雄激素积累的HVc神经元是否投射到其他发声控制核团。我们在这里报告，两个主要的传出投射从HVC（到X区和粗核的archistriatum）包括相当大比例的雄激素积累神经元。这些数据是一致的假设，即雄激素积累的程度，在HVc可能反过来调节雄激素敏感性的其他歌曲区域。
In zebra finches, androgens stimulate sing production and promote growth of the neural regions controlling song. Early exposure to estrogen establishes this sensitivity to androgens and increases the number of androgen-accumulating cells in two song regions, the hyperstriatum ventralis pars caudalis (HVc) and the anterior neostriatum. To examine if these regional changes in androgen accumulation could directly influence androgen responsiveness elsewhere in the song system, we combined autoradiographic and retrograde tracing techniques to determine if androgen-accumulating HVc neurons project to other vocal control nuclei. We report here that both major efferent projections from HVc (to Area X and the nucleus robustus of the archistriatum) include a substantial proportion of androgen-accumulating neurons. These data are consistent with the hypothesis that the extent of androgen accumulation in HVc may in turn regulate the androgenic sensitivity of other song regions.