Increasing cortical activity in auditory areas through neurofeedback functional magnetic resonance imaging

Increasing cortical activity in auditory areas through neurofeedback functional magnetic resonance imaging
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DOI:
10.1097/01.wnr.0000227996.53540.22
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发表时间:
2006-08-21
期刊:
影响因子:
1.7
通讯作者:
Jolesz, Ferenc A.
Jolesz, Ferenc A.
中科院分区:
医学4区
文献类型:
--
作者:
Yoo, Seung-Schik;O'Leary, Heather M.;Jolesz, Ferenc A.

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我们报告了一种功能性磁共振成像方法,可将特定任务的大脑活动作为生物反馈信号提供,以指导个体在声音刺激期间增加听觉区域的皮层活动。研究参与者总共接受了多次功能磁共振成像扫描,而初级和次级听觉区域内激活的皮质体积的变化会在扫描期间反馈给他们。根据反馈信息,参与者尝试通过调整对听觉刺激的注意力水平来增加后续试验期间重要体素的数量。结果显示,收到反馈的一组人能够比对照组更大程度地增加激活量和血氧水平依赖性信号。
We report a functional magnetic resonance imaging method to deliver task-specific brain activities as biofeedback signals to guide individuals to increase cortical activity in auditory areas during sound stimulation. A total of I I study participants underwent multiple functional magnetic resonance imaging scan sessions, while the changes in the activated cortical volume within the primary and secondary auditory areas were fed back to them between scan sessions. On the basis of the feedback information, participants attempted to increase the number of significant voxels during the subsequent trial sessions by adjusting their level of attention to the auditory stimuli. Results showed that the group of individuals who received the feedback were able to increase the activation volume and blood oxygenation level-dependent signal to a greater degree than the control group.